Squalane + Retinol Night Serum

Advanced retinol + retinal serum that improves fine lines, blemishes and dark spots with minimal irritation.

287 reviews
Bestseller Squalane + Retinol Night Serum
  • Squalane + Retinol Night Serum
  • Squalane + Retinol Night Serum
  • Squalane + Retinol Night Serum
  • Squalane + Retinol Night Serum
  • Squalane + Retinol Night Serum
  • Squalane + Retinol Night Serum
  • Squalane + Retinol Night Serum
  • Squalane + Retinol Night Serum

Squalane + Retinol Night Serum

Advanced retinol + retinal serum that improves fine lines, blemishes and dark spots with minimal irritation.

287 reviews

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Due to international regulations, this product cannot be shipped outside the U.S.

  • Cruelty Free Cruelty Free

    Cruelty Free

  • Nontoxic Nontoxic

    Nontoxic

  • Paraben free Paraben free

    Paraben free

  • PEG free PEG free

    PEG free

  • Vegan Vegan

    Vegan

An innovative formula with an encapsulated duo of time-release retinol and retinal, working to improve the appearance of fine lines and wrinkles, discoloration, and texture, with minimal irritation.  Paired with a squalane and saffron antioxidant blend to hydrate skin & boost radiance.

  • Effective retinol serum for sensitive skin types made with non-irritating, sustainably-sourced ingredients, including squalane, saffron, rosemary, sunflower, rice bran and vitamin E.
  • Optimized by both squalane and an antioxidant blend to help deliver and enhance the results of the retinol and retinal, keeping the skin hydrated, with minimal irritation.
  • Time release technology, squalane and a powerful blend of antioxidants, proves to be an effective delivery system that allows the retinoids to penetrate more deeply into the skin while being gradually released over 8 hours, gently delivering dramatically visible results.

Shop all clean facial serums.


Retinoids are not recommended for those pregnant or nursing; always consult a physician before using new products.

  • Cruelty Free Cruelty Free

    Cruelty Free

  • Nontoxic Nontoxic

    Nontoxic

  • Paraben free Paraben free

    Paraben free

  • PEG free PEG free

    PEG free

  • Vegan Vegan

    Vegan

Clinical Report

% Confirm

  • 100% noticed their wrinkles appeared smoother*
  • 100% noticed an improvement in uneven skin tone**
  • 100% noticed a visible increase in skin firmness***

Directions:

  • Apply pea-size amount to clean, dry skin at night.

  • Start by using 2x per week and gradually increase.

  • Apply sunscreen the following morning after use.
RETINOL + RETINAL COMPLEX
  • SQUALANE: Derived from sugarcane, it mimics body's natural hydrating oils to provide weightless moisture to deliver active ingredients deep into the skin and prevent overdrying.
  • ANTIOXIDANT BLEND: A blend of sustainably-sourced Saffron, Rosemary, Sunflower, and Rice Bran extracts plus Vitamin E, provide antioxidant protection and help to minimize irritation and support overall skin health, including texture, aging and blemishes.

All Ingredients:

Water/Aqua/Eau, Squalane, Glycerin, Caprylic/Capric Triglyceride, Cetearyl Olivate, Sorbitan Olivate, Retinol, Retinal, Allantoin, Crocus Sativus Stigma Extract, Pseudozyma Epicola/Evening Primrose Oil Ferment Extract, Tocopherol, Rosmarinus Officinalis (Rosemary) Leaf Extract, Oryza Sativa (Rice) Bran Extract, Cetearyl Alcohol, Helianthus Annuus (Sunflower) Extract, Hydroxyapatite, Dextrin, Carbomer, Sodium Gluconate, Phenoxyethanol, Ethylhexylglycerin, Sodium Hydroxide

  • Retinoids are the group of Vitamin A derivatives that have been proven to stimulate cell renewal, increase collagen production and improve collagen density. The active ingredient of Vitamin A is retinoic acid. Your skin is only able to use retinoids that are—or can be converted to—retinoic acid, because retinoic acid works by binding to retinoic acid receptors found on the outer membrane of cells. This serum contains two powerfully gentle retinoid ingredients, retinaldehyde and retinol. Retinaldehyde needs only one conversion to retinoic acid in the skin. Retinol goes through two conversions, first to retinaldehyde then it is converted to retinoic acid. The retinaldehyde in this formula is time released to ensure maximum stability and absorption while allowing the Vitamin A active to be released gradually into the skin while you sleep for minimal irritation.
  • We recommend this serum in evening use because retinol and retinal can cause sensitivity to the sun. It is also important to wear a daily sunscreen every morning and reapply during the day.
  • Yes, our Squalane + Retinol Night Serum is made with sustainably-sourced ingredients that are safe for people and the planet. This serum is best for those concerned with signs of aging, including fine lines, wrinkles and uneven skin tone. Can be used as a preventative and corrective treatment. It should not be used while pregnant.
  • We recommend using Squalane + Retinol Night Serum in the evening and choosing a day serum, like our Squalane + Vitamin C Dark Spot Serum or Squalane + Copper Peptide Serum. Be sure to start using a small, pea size quantity of retinol when starting out, even alternating between the nights used. Since our retinol is a powerful serum, we don't recommend layering with other treatment products, but encourage you to layer with other moisturizers and oils.
  • Retinol and retinal work together to increase performance and minimize irritation of the skin for powerful, yet gentle results.

CUSTOMER REVIEWS CUSTOMER REVIEWS

Customer Reviews
4.5 Based on 287 Reviews
5 ★
61% 
175
4 ★
31% 
90
3 ★
5% 
14
2 ★
1% 
4
1 ★
1% 
4
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A
03/17/2023
Amy

Not impressed

For the price point I thought this would have been a great night time serum but using it regularly I see no difference and the packaging isn’t the best. The top(pump) basically comes off every time you take the cap off. It is a very gental retinol so those that have more sensitive skin this make work really well for. I have been using chemical exfoliants for yrs soy skin isore seasoned

  • Skin Type Combination
  • Top Concern Fine Lines & Wrinkles
  • Age 25-34
03/20/2023

Biossance

Thank you for sharing your experience with us! Please email our Customer Care team at customercare@biossance.com or reach out to us on LiveChat so we can better assist you. We are more than happy to help you out with selecting the right products for your skin type. The Biossance Team

A
03/14/2023
Andrea
United States United States

Dries me out

I bought this to try when I first saw it come out, and began using it three weeks ago.. once I ran out of the Phyto-retinol... I have previously used retinol years and years ago... With the highest available concentration over the counter, with those I typically peel the first few uses and then adjust with out any further irritation. During my three weeks I still wake up with dry patches after use (use it 3x a week), and I find I am now sensitive or feel a burning sensation when I use dark spot Vit C, lactic acid between uses or when I use this retinol. Maybe it's to do with my age, but I never experienced this before and this retinol is the only new thing I added to my regime. I plan to give it another week, it does noticably work, but I already have dry skin and this formula is making me sensitive to my other products and a constant red hue.

  • Skin Type Dry
  • Top Concern Fine Lines & Wrinkles
  • Age 35-44
03/15/2023

Biossance

Thank you for telling us about your experience. We are so sorry you have had a negative experience with the Squalane + Retinol Night Serum. All of our products are formulated to the highest standards of safety and are thoroughly tested, and we always recommend a patch test prior to use. Unfortunately, you may have a personal sensitivity to an ingredient in the product. No matter how gentle something is, there may be a few people who can’t use it. We understand that one of our advisors from our customer care team will be in touch with you and are so glad that they will be able to support you in your journey to resolve this issue! The Biossance Team

A
03/12/2023
Anonymous
United States United States

Gentle

This is my first retinol product I've tried and I was prepared for all the phases of starting a retinol but I honestly have not had much discomfort with this product. I think I'm going on week 3 and I'm seeing a change in my skin and I'm pleased.

  • Skin Type Combination
  • Top Concern Uneven Tone & Dark Spots
  • Age 35-44
S
03/10/2023
Sarah
United States United States

Great regular retinoid

This stuff works great once your skin is used to it. I have sensitive skin and really had to start slow (1x a week for several weeks before building up), but after that, it really does brighten and tone the skin!

  • Skin Type Sensitive
  • Top Concern Uneven Tone & Dark Spots
  • Age 25-34
A
03/09/2023
Anonymous
United States United States

LOVE!

Love the night serum! I put this on every night to exfoliate because it leaves my skin feeling so smooth without any irritation.

  • Skin Type Dry
  • Top Concern Blemishes
  • Age 25-34

OUR SUSTAINABILITY PROMISE

Our commitment to people and planet applies to everything we create. We innovate every aspect of our company and supply chain to do better for our world and be the leading pioneers in sustainable beauty.

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  • RENEWABLE RESOURCES

    Our squalane is derived from renewable sugarcane.
  • PLANET-FIRST PROCESSES

    Formulated using the latest sustainable methods. No deforestation and developed in far proximity from rainforests. Low water usage.
  • CONSCIOUS PACKAGING

    Sugarcane and Forest Stewardship Council-certified boxes (FSC).
  • SAFE PRODUCTS

    Vegan, cruelty-free and nontoxic for people and the environment.
    Vegan Vegan VEGAN Cruelty Free Cruelty Free CRUELTY
    FREE
    Paraben free Paraben free PARABEN
    FREE
    Nontoxic Nontoxic NONTOXIC Synthetic fragrance free Synthetic fragrance free FRAGRANCE
    FREE
    Synthetic fragrance free Synthetic fragrance free SYNTHETIC
    FRAGRANCE
    FREE
    FSC certified wood FSC certified wood FSC
    CERTIFIED
    WOOD
    Baking soda free Baking soda free BAKING
    SODA FREE
    PEG free PEG free PEG FREE
  • READY TO RECYCLE

    All of our inner and outer cartons. (This excludes our airless bottle components and pumps.) We are working towards more sustainable solutions.