Squalane + Phyto-Retinol Serum

Plant-derived retinol serum with niacinamide that fights signs of aging

577 reviews
  • Bottle of Squalane + Phyto-Retinol Serum
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  • before and after use Squalane + Phyto-Retinol Serum
  • Dispenser of Squalane + Phyto-Retinol Serum
  • Squalane + Phyto-Retinol Serum
  • Bakuchiol vs Retinol chart
  • layering guide
  • Old and new product
  • Squalane + Phyto-Retinol Serum in shower
  • cream
  • Full sizeSize: 30mL/1oz

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  • EWG

  • Vegan

  • Cruelty Free

  • Nontoxic

  • Paraben free

  • Synthetic fragrance free

  • PEG free

Clinical Report

% Confirm

  • 100% agreed product felt gentle on the skin, but powerful on wrinkles*
  • 100% saw a visible improvement in wrinkles**
  • 100% agreed fine lines appear smoother***
You asked, we listenedthe packaging of your favorite serum just got an upgrade.
Our lightweight, powerfully effective serum is now housed in an innovative, ultra-light bottle with our 100% recyclable, airless pump that dispenses every last drop of product. Featuring bakuchiol, a plant-derived alternative to retinol, and niacinamide, our anti-aging serum reduces the look of lines and wrinkles while visibly firming skin without irritation or sensitivity.
This squalane serum formula was clinically evaluated and found to be non-irritating and effective for all skin types*.

If you thought you couldn’t get the benefits of retinol and niacinamide, think again.

  • Reduces the look of fine lines & wrinkles
  • Visibly improves firmness
  • Evens the look of skin tone
  • Plant-based alternative to retinol—bakuchiol
  • Features our 100% recyclable, airless pump that dispenses every last drop
  • 70% lighter packaging made from post-consumer recycled plastic to help minimize our carbon footprint through reducing carbon emissions in transit

For external use only. Use only as directed. We recommend a patch test prior to use if you are particularly sensitive. If irritation occurs, consult a dermatologist.

  • EWG

  • Vegan

  • Cruelty Free

  • Nontoxic

  • Paraben free

  • Synthetic fragrance free

  • PEG free


  • Massage 1-2 pumps of the squalane serum onto clean face and neck, morning and night.


Layering Guide:

  • Step 1: Cleanser
  • Squalane + Elderberry Jelly Cleanser
  • Squalane + Antioxidant Cleansing Oil
  • Squalane + Amino Aloe Gentle Cleanser
  • Step 2: Toner
  • Squalane + BHA Pore Minimizing Toner
  • Step 3: Mask
  • Squalane + Glycolic Renewal Facial
  • Step 4: Eye Treatment
  • Squalane + Peptide Eye Gel
  • Squalane + Marine Algae Eye Cream
  • Step 5: Treatment
  • Squalane + Phyto-Retinol Serum
  • Squalane + Lactic Acid Resurfacing Night Serum
  • Squalane + Vitamin C Dark Spot Serum
  • Step 6: Moisturizer
  • Squalane + Omega Repair Cream
  • Squalane + Probiotic Gel Moisturizer
  • Step 7: Oil
  • 100% Squalane Oil
  • Squalane + Vitamin C Rose Oil
  • Squalane + Tea Tree Balancing Oil
  • Step 8: Sunscreen
  • Squalane + Zinc Sheer Mineral Sunscreen
  • Step 9: Makeup
  • Apply foundation, BB/CC creams and any color cosmetics
  • Anytime: After Step 1, Over Makeup, or Throughout the Day
  • Squalane + Omega Repair Hand Cream
  • Squalane + Hyaluronic Toning Mist
  • Squalane + Rose Vegan Lip Balm
  • SQUALANE: Derived from sugarcane, it mimics body's natural hydrating oils to provide weightless moisture to deliver active ingredients deep into the skin and prevent overdrying.
  • Niacinamide: Helps even out skin tone, improves skin barrier function and skin texture

All Ingredients:

Water/Aqua/Eau, Squalane, Glycerin, Niacinamide, Sodium Acrylates Copolymer, Bakuchiol, Sodium Hyaluronate, Rosa Canina Fruit Oil, Citrus Aurantium Amara (Bitter Orange) Peel Oil, Biosaccharide Gum-1, Lecithin, Hexylene Glycol, Ethylhexylglycerin, Caprylyl Glycol, Phenoxyethanol, Sodium Gluconate, Citric Acid, Linalool, Geraniol, Limonene

  • 1What does "phyto" mean?

    Phyto comes from the Greek word “phyton” which means “plant”. When you see the word “phyto” it means that the product or ingredient comes from a plant source. We call our serum Phyto-Retinol because the main ingredient, bakuchiol, is a plant-derived retinol alternative.
  • 2How does bakuchiol work like retinol? How do you get the same benefits without the irritation?

    Bakuchiol works by mimicking the beneficial activity of retinol. In clinical studies, bakuchiol was found to target several of the same gene expression receptors as retinol, and had similar effects on boosting Collagen I, II and III. Bakuchiol also has strong antioxidant properties and is suitable for daytime use, unlike retinol.
  • 3Does Squalane + Phyto-Retinol Serum have the same restrictions as traditional retinol?

    No, the product is free of retinol or retinoids. The “retinol-like” effects come from bakuchiol, a plant-derived retinol alternative that has similar benefits, but because it works in a different way, doesn’t have the irritation or sun sensitivity associated with retinol.
  • 4How much PCR%, why not 100%?

    Our new component is made from 50% PCR and is 100% curbside recycle ready - this is the highest percent of PCR we are able to include without compromising the performance of the packaging or its recyclability. Our priority was to deliver a better user experience that minimized waste, increased recyclability, and lowered our carbon footprint.
  • 5How do I ensure I have removed all product?

    We have switched to an airless pump component to minimize product waste left in the component. To remove the pump and ensure you have used up all product, simply pull off the white pump cap and remove the copper pump - if difficult to remove by hand, a pair of pliers will do the trick!
  • 6Is this Squalane + Phyto-Retinol Serum safe to use during pregnancy or breastfeeding?

    Since Squalane + Phyto-Retinol Serum does not contain any retinol or retinoids, it does not have the same contraindications as retinol. However, as with any product applied to the skin we recommend checking with your doctor before using while pregnant or breastfeeding.


Customer Reviews
4.3 Based on 577 Reviews
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Erin S.
United States United States


Always notice a difference when I stop using this serum. Love the smooth texture it gives my skin after a night of sleep!

  • What is your skin type? Dry
  • What skin issue concerns you most? Redness & Sensitivity
  • How old are you? 25-34
United States United States

Retinol serum

So far so good. I haven’t been using this product for long, but so far so good.

  • What is your skin type? Combination
  • What skin issue concerns you most? Redness & Sensitivity
  • How old are you? 45-54
Michelle A.
United States United States

Cannot live without this serum!

I am obsessed with the texture and results of this formula! My skin is super sensitive and acne prone, it has helped to even out my skin discoloration. I recommend this to everyone on I know!

  • What is your skin type? Sensitive
  • What skin issue concerns you most? Uneven Tone & Dark Spots
  • How old are you? 25-34
United States United States

Love this

Ever since using this it has improved my skin immensely! I would recommend this to everyone. It is really light feeling and effective, not sticky. I love all Biossance products!

  • What is your skin type? Dry
  • What skin issue concerns you most? Redness & Sensitivity
  • How old are you? 35-44
Jocelyn P.
United States United States

Best sensitive skin-friendly retinol, EVER

I own all Biossance products, yes ALL (except the Lactic Acid, because my skin just don't tolerate lactic acids in general). This retinol is a game changer, won't cause irritation or "rash" on skin, is pretty gentle but highly effective! Within a week you will notice your skin getting better and better, and swelling from breakouts will fade. I use it at night, after the Squalane-Hyaluronic toner and then seal it with the Squalane-Omega repair cream and Squalane+Vitamin C Rose oil. This retinol is a MUST.

  • What is your skin type? Sensitive
  • What skin issue concerns you most? Blemishes
  • How old are you? 25-34


Our commitment to people and planet applies to everything we create. We innovate every aspect of our company and supply chain to do better for our world and be the leading pioneers in sustainable beauty.


    Our squalane is derived from renewable sugarcane.

    Formulated using the latest sustainable methods. No deforestation and developed in far proximity from rainforests. Low water usage.

    Sugarcane and Forest Stewardship Council-certified boxes (FSC).

    Vegan, cruelty-free and nontoxic for people and the environment.

    All of our inner and outer cartons. (This excludes our airless bottle components and pumps.) We are working towards more sustainable solutions.
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