100% Squalane Oil

Our sustainable, vegan multitasker that hydrates head to toe—now in special jumbo size

839 reviews
New Jumbo Size
  • 100% Squalane Oil
  • 100% Squalane Oil
  • 100% Squalane Oil
  • play-video
  • 100% Squalane Oil
  • 100% Squalane Oil
  • 100% Squalane Oil
  • 100% Squalane Oil
  • 100% Squalane Oil
  • Jumbo sizeSize: 200mL/6.7oz
  • Full sizeSize: 100mL/3.3oz
  • Travel sizeSize: 12mL/0.4oz
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  • EWG

  • Vegan

  • Cruelty Free

  • Nontoxic

  • Paraben free

  • Fragrance free

  • PEG free

Clinical Report

% Confirm

  • 95% agree skin felt instantly hydrated*
  • 95% agree skin appeared softer and smoother after 7 days*
  • 94% agree that it quickly and easily absorbs into the skin*
This is the powerhouse ingredient at the heart of every Biossance formula. It’s bioidentical to the moisture found in human skin, making it weightless and instantly absorbed and perfect for use all over the body. Our squalane is derived from sustainable sugarcane, a purer, vegan, more ethical, and more effective version than other forms of squalane. And since it replaces the need for similar moisture taken from the livers of sharks, it saves 2 million of these critical apex predators per year.
The new special jumbo size and packaging celebrates sharks and our mission to keep this critical species safe.

  • Squalane oil for the face instantly hydrates and locks in essential moisture.
  • Helps other active ingredients penetrate more deeply and work more effectively
  • Promotes microbiome diversity for healthier-looking skin
Shop all clean moisturizers & oils.

This 100% pure squalane facial oil is for external use only. Use only as directed. Avoid eye area. We recommend a patch test prior to use if you are particularly sensitive. If irritation occurs, consult a dermatologist.

  • EWG

  • Vegan

  • Cruelty Free

  • Nontoxic

  • Paraben free

  • Fragrance free

  • PEG free


    • Squalane Oil For Face: Rub a small amount of pure squalane oil together between hands to warm. Pat gently onto face, neck and décolleté.
    • Squalane Oil For Body: Massage a few pumps onto skin immediately after showering, paying close attention to areas needing extra hydration like arms, legs, and knees.
    • Squalane Oil For Hair: Rub a small amount of pure squalane oil between hands and smooth through dry or wet hair to add shine and tame flyaways, split ends and frizz.
    • Adjust amount as needed.


    • If your skin is on the oilier side, slightly dampen skin with Micronutrient Fine Mist or water and then gently massage in squalane oil for face.

Layering Guide:

  • Step 1: Cleanser
  • Squalane + Elderberry Jelly Cleanser
  • Squalane + Antioxidant Cleansing Oil
  • Squalane + Tea Tree Cleansing Gel
  • Step 2: Toner
  • Squalane + BHA Pore Minimizing Toner
  • Step 3: Mask
  • Squalane + Glycolic Renewal Facial
  • Step 4: Eye Treatment
  • Squalane + Peptide Eye Gel
  • Squalane + Marine Algae Eye Cream
  • Step 5: Treatment
  • Squalane + Phyto-Retinol Serum
  • Squalane + Lactic Acid Resurfacing Night Serum
  • Squalane + Vitamin C Dark Spot Serum
  • Step 6: Moisturizer
  • Squalane + Omega Repair Cream
  • Squalane + Probiotic Gel Moisturizer
  • Step 7: Oil
  • 100% Squalane Oil
  • Squalane + Vitamin C Rose Oil
  • Squalane + Tea Tree Balancing Oil
  • Step 8: Sunscreen
  • Squalane + Zinc Sheer Mineral Sunscreen
  • Step 9: Makeup
  • Apply foundation, BB/CC creams and any color cosmetics
  • Anytime: After Step 1, Over Makeup, or Throughout the Day
  • Squalane + Omega Repair Hand Cream
  • Squalane + Hyaluronic Toning Mist
  • Squalane + Rose Vegan Lip Balm
Squalane oil

All Ingredients:

  • 1Where does your 100% Squalane come from? Why sugarcane and not olives?

    Traditionally Squalane was harvested from shark liver, though our scientists spent years developing pure Squalane from 100% plant-based, renewable sugarcane. The quality of Squalane produced from olives depends on unreliable factors like weather and crop growth. The quality and purity of our sugarcane Squalane is stable and cost effective.
  • 2What is the difference between SqualAne and SqualEne?

    The human body produces SqualEne. Squalene is part of our skin’s own natural moisture, but the amount made and retained in your skin decreases over time. Our SqualAne is a hydrogenated version of Squalene which makes it safer and skin-friendlier! Additionally, our sugarcane-derived Squalane is a sustainable alternative to the historical production method of squalene from shark liver. Our background in biotechnology allows us to create products that are clean and free of potentially harmful ingredients, as well as being sustainably sourced.
  • 3What’s the difference between 100% Squalane Oil and Squalane + Vitamin C Rose Oil? Do I need both?

    While they both contain super hydrating Squalane, our Vitamin C Rose Oil also contains...(you guessed it!) Vitamin C and rose essential oil, making it suitable for facial use. Our 100% Squalane Oil can be used head-to-toe as an all-over body, face and hair hydrator.


Customer Reviews
4.8 Based on 839 Reviews
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Brianna M.
United States United States

Good product but the packaging is terrible and leaks out. It’s pretty upsetting when the product is expensive and is wasted so easily.

  • What is your skin type? Dry
  • What skin issue concerns you most? Dry Skin
  • How old are you? 18-24

Hello Brianna! Thank you for sharing your experience with us! This may be a Quality issue with the particular 100% Squalane Oil bottle you have received. We will record the batch number for our records! On April 21, 2021 we announced the formation of an alliance with four other fantastic brands that are equally committed to sustainability… Ren, Caudalie, Herbivore, and Youth To The People. Together, we have pledged to significantly and rapidly reduce packaging waste by the year 2025, in an effort to create meaningful positive change and help negate the environmental crisis regarding packaging waste, almost 70% of which currently ends up in landfills in the US. At Biossance, we have always believed a rising tide lifts all ships. Especially when it comes to the fight for our planet, we are stronger together. Sustainability Alliance Leaders will meet regularly to share resources, ideas, and solutions to some of the beauty industry's biggest sustainability challenges. Our first two points to tackle are single-use samples and non-recyclable pumps. We also plan to host open discussions on Clubhouse and consumer masterclasses and activities for World Oceans Day. Additionally, we’ll be partnering with Sephora to inspire our passionate community of changemakers to be more eco-conscious. We at Biossance are taking specific actions towards sustainability as well : Saving Sharks through our Partnership with Oceana, Always leading with Clean Ingredients and Formulations. We commit to Conscious Packaging, Carbon Neutral Shipping and Zero Waste by 2025. I will ask someone from our Customer Care Team reach out and help resolve this issue today! Have a wonderful day! The Biossance Team

United States United States
Very oily

I really wanted to love this oil. Followed instructions to apply the oil after layering the products on first and put the oil last...but it’s way to oily and shiny on my face. I have dry skin and it’s still way too oily for daytime and doesn’t absorb into the skin. Best for nighttime routine.

  • Skin Type Dry
  • Top Concern Dry Skin
  • Age 55+

Hello Jeanine! Thank you for sharing your experience with us! We are sorry to hear you did not love our 100% Squalane Oil! This is a top selling item for us! We understand everyone's skin is so uniquely different, this sounds like it was not a match for your skin needs. I will have one of our esthetician's from our customer care team be in touch with you. We are so glad they will be able to support you in your journey to resolve this issue! You can also reach out to us instantly on LiveChat or Video Chat by finding the gray chat bubble on the bottom right of Biossance.com. If you purchased this on Biossance.com please visit biossance.com/a/returns to return the product. Thank you & have a wonderful day, The Biossance Team

United States United States

Skin is softer. Easy to apply, not heavy and sticky. Looove it!!

  • What is your skin type? Dry
  • What skin issue concerns you most? Dry Skin
  • How old are you? 55
United States United States
Just great

This is just the right amount of moisture for my skin, and good for layering too. Seems lighter/better absorbed than other squalane I've tried.

  • What is your skin type? Combination
  • What skin issue concerns you most? Blemishes
  • How old are you? 35-44
L. Mattingly
United States United States

I have tried the probiotic gel, the moisturizer and the oil. Over a 2 week period, I found a noticeable difference in my skins elasticity after using the oil. I decided to do an experiment, and use it on the sagging appearance of the skin just above my knees. Remarkably, this skin looks a lot more youthful. I would recommend the oil!

  • Skin Type Normal
  • Top Concern Age Prevention
  • Age 45-54


Our commitment to people and planet applies to everything we create. We innovate every aspect of our company and supply chain to do better for our world and be the leading pioneers in sustainable beauty.


    Our squalane is derived from renewable sugarcane.

    Formulated using the latest sustainable methods. No deforestation and developed in far proximity from rainforests. Low water usage.

    Sugarcane and Forest Stewardship Council-certified boxes (FSC).

    Vegan, cruelty-free and nontoxic for people and the environment.

    All of our inner and outer cartons. (This excludes our airless bottle components and pumps.) We are working towards more sustainable solutions.
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